Protein degradation via ubiquitination is a major proteolytic mechanism in cells.Once a protein is destined for degradation, it is tagged by multiple ubiquitin molecules.The synthesised polyubiquitin chains can be recognised by the 26S proteosome where proteins are degraded.These chains form through multiple ubiquitination cycles that are similar t

Retroperitoneal liposarcoma presenting as an inguinal hernia is extremely chainsaw file rare without specific clinical findings and laboratory abnormalities; it might mislead the surgeon for the diagnosis and the following decision.This study is to report our experience of a large retroperitoneal liposarcoma presenting as an irreducible inguinal he

Building envelope systems that integrate Phase Change Materials (PCMs) are solutions aimed at increasing the thermal energy storage potential of the building envelope while keeping its mass reasonably low.Building envelope components with PCMs can be either opaque or transparent and can be based on different types of PCMs and integration methods.In

The axial fan blades used in underground mines are usually manufactured in AlSi12CuMgNi alloy (EN AC 48000).They must have a high mechanical strength to withstand the stresses resulting from the rotation speed of the rotor and a high resistance to erosive wear caused by beetroot birkenstock suspended particles from underground mining and transport